CDC42 and its different expression in beings and different tissues

Mohammad Nabiuni¹ Mona Motaharinia²

1) Department of Biology, Faculty of Science, Kharazmi university,Tehran, Iran; email:
2) Department of Biology, Faculty of Science, Kharazmi university,Tehran, Iran; email:

IOI Code : XYEZ-AHCKZ
Publication : International Conference On Research Science And Technology(rstconf.com)
Abstract :
    Cdc42, a member of GTPaseRho which belongs to Ras super family. For this, first we separately received the ESTs of cancerous and normal tissues of intestine, gastric, ovarian, prostate, and lung from NBCI reference site and DDD part and put in rank by cdc42 gene and the help of Blast stand alone program. Also we received this gene in 7 different species of animals and draw their evolutionary trees. On the other hand, the product structure of the gene was predicted with the help of online programs. It been clear that during the evolution,the structure of these gene is highly protected which show the importance of this gene and its activity in different beings . On the other hand, the catalytic place and interaction of the protein were identified and it was found that these proteins have aliphatic index and isoelectric close point in different beings. The end exons in different modifications have the highest expression. The three-dimensional structure of the gene product contains an alpha helix and beta plate. molecular, isoelectric point, index of aliphatic and evolutionary tie in human species was found nearby.

Keywords : cdc42 est blast stand alone exon