Synergistic ‎Effect of TiO‎2‎‏,‏‎ CeO‎2‎‏ ‏and ‎GQD Nanoparticles on‎ ‎The Photoelectrochemical Detection of Dopamine

Nasrin Ahmadi¹ Mojtaba Bagherzadeh² Ali Nemati³

1) Department of Materials Engineering, Science and Research Branch, Islamic Azad University, Tehran,‎ Iran, E-mail:
2) Reactor and Nuclear Safety School, Nuclear Science and Technology Research Institute, 81465-1589, ‎Isfahan, Iran, E-mail:
3) Department of Materials Science & Engineering, Sharif University of Technology, Tehran, Iran, E-mail:

Publication : 13th Biennial Electrochemistry Seminar of Iran(elect13pguac.ir)
Abstract :
Due to basically role of dopamine (DA) in some diseases like Parkinson and Schizophrenia, its ‎determination is important and thus, it is desirable to develop new, simple and rapid analytical methods ‎for the determination of DA with high selectivity and sensitivity, especially for diagnostic applications ‎‎[1-2]. Recently, developments in nanotechnology and preparations of semiconductor nanomaterials ‎cause open a new field in photoelectrochemical methods based on nanosemiconductors for ‎determination of DA [3]. In the present work, new nanocomposites with semiconducting property from ‎TiO‎2‎‏,‏‎ CeO‎2‎‏ ‏and ‎Graphene quantum dot‏ (GQD) ‎‏nanoparticlesare synthesized [4‎‏-‏‎5] and ‎the‎ ‎photoelectrochemical responses of a modified glassy‎ carbon electrode‏ (GCE) ‏with them, are evaluated ‎by electrochemical methods. ‏Photoelectrochemical measurements were performed using a P/G ‎stat ‏device‎ ‎and recorded by a conventional tree-electrod system‎ (modified ‎GCE, Ag/AgCl and Pt wire‎) that ‎equipped with a 360 W halogen lamp (Visible wavelength ‎range‎), in 0.1 M PBS solution and bias ‎potential as 0.0 V.‎‏ ‏The modified electrodes showed outstanding response in the present of light in ‎comparison to dark condition towards DA. Affecting parameters like pH, bias potential and DA ‎concentration on photoelectrochemical responces of the modified electrodes were studied. Linear ‎ranges, figure of merits and detection limits of the modified electrodes by the prepared semiconductors ‎were calculated and compared with together. The best result was observed for a modified GCE with ‎TiO‎2/CeO‎2/GQD‏ ‏in a wide linear range, 0.3-750 μM, with detection limit as 0.022 μM. Observed results ‎will be presented and discussed here for the first time.‎
Keywords : Photoelectrochemical sensor Dopamine Synergistic effect TiO‎2 CeO‎2‎ Graphene quantum dot.‎‏