Evaluation of pulmonary bacterial infections in people exposed to mustard gas

Farzam Fathi¹ Zahra Nasirzadeh² Saeid Ferdousmakan³ Helia Khodabakhsh⁴ Afshin Souri⁵ Seyed Mohammad Ghorbani Dazmiri⁶ Seyed Amir Hosseini⁷

1) Department of Microbiology, Faculty of Science, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran
2) Department of Microbiology, Faculty of Science, Rasht Branch, Islamic Azad University, Rasht, Iran
3) Department of Pharmacy Practice, Nargund College of Pharmacy, Bangalore 560085,India
4) Department of Cell and Molecular Biology, Islamic Azad University, Tehran Medical Branch, Tehran, Iran
5) Department of Public Management, Faculty of Management, University of Malayer, Hamadan, Iran
6) Faculty of Biological Sciences, Sari Branch, Islamic Azad University, Sari, Iran
7) Islamic Azad University of Kermanshah Medical Sciences Branch, Kermanshah, Iran

Publication : 6th International Conference on Applied Researches in Science & Engineering - Germany(6carse.com)
Abstract :
Mustard gas (MG) exposure can cause several injuries including organs impairment and alter the normal functions of biological systems. In this study, we have studied the pulmonary bacterial infections (PBI) of Iranian people who exposed to MG. One hundred and one patients who were exposed to MG and 110 healthy controls were included in the study. Direct smear from the lung specimens was prepared and stained with different staining methods. To culture the specimens, the routine culture media were used. PCR was carrying out for some of specimens suspected to Mycobacterium tuberculosis. Of 101 patients and 110 controls, 45.54% and 19.09% were positive for PBI, respectively. Two patients were also infected with Mycobacterium tuberculosis that was proven by PCR. These findings indicate a high prevalence of PBI in patients exposed to MG, suggesting that these patients are more susceptible to opportunistic bacterial infection and precautions should be applied to these people
Keywords : PCR Mustard gas Pulmonary bacterial infections