Comparison of the effect of 8 weeks of endurance training on serum levels of selenoprotein P in people with diabetes

Farnaz seifi¹ Nabil Niyazi Camel²

1) 1. Associate Professor of Sports Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran
2) 2. Master s student, Faculty of Educational Sciences and Psychology, Mohaghegh Ardabili University, Ardabil, Iran

Publication : Second International Exercise Physiology Conference(sportuma2023.ir)
Abstract :
Abstract Diabetes is one of the common metabolic diseases. In studies related to the pathology of diabetes, a positive correlation between SeP serum levels has been confirmed. Endurance sports activity has an effect on controlling hyperglycemia and improving glucose metabolism by interfering with the regulation of insulin receptors and overexpression of glucose transporters. The main aim of the present study is to investigate the effect of 8 weeks of resistance and endurance training on SeP serum levels. This research included 20 type 2 diabetic patients who underwent endurance training in two control groups of 10 people in Ardabil city. Blood sampling around 8 am after fasting for at least 8 hours in order to measure the levels of liver enzymes, insulin, glucose, cholesterol, triglyceride, HbA1c and lipid profile as well as the main research variables including Fetuin-B, ANGPTL4 and LPL in the central laboratory Ardabil University was conducted. Endurance training consisted of 8 weeks of walking or running on a treadmill with an intensity of 50-75% of the target heart rate, which the subjects participated voluntarily. After the end of the course, blood was taken as before. Correlated t-test and one-way ANOVA were used to compare the amount of changes between pre-test and post-test and to compare between training and control groups. All analyzes were performed using SPSS version 23 statistical software and were considered statistically significant (P<0.05). Increasing the volume of the exercise program, especially the resistance feature of the exercise modality in diabetic people, plays an important role in controlling SepP and controlling the vascular damage of this marker, which plays a significant role in reducing the risk factors and cardiovascular damage caused by diabetes.
Keywords : diabetes insulin endurance training protein