Experimental investigation and modeling of baby hamster kidney cell growth for foot and mouth virus vaccine production

mahmoud hasani¹ reza golhosseini² seyed mahmoud azimi³ mahdi arjmad⁴ homayon mahravani⁵ shahriar salemi⁶

1) Department of Chemical Engineering, Faculty of Engineering, University of Kashan, Kashan,
2) Department of Chemical Engineering, Faculty of Engineering, University of Kashan, Kashan,
3) Foot and Mouth Disease Reference Laboratory, Razi Vaccine & Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran-
4) Department of Chemical Engineering, Tehran South Branch, Islamic Azad University,
5) Foot and Mouth Disease Reference Laboratory, Razi Vaccine & Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj,
6) Department of Chemical Engineering, Faculty of Engineering, Science and Research Branch , Islamic Azad University , Tehran ,

Publication : 4th International Congress on Engineering, Technology and Applied Science - Auckland University of Technology(etas2019.com)
Abstract :
Baby hamster kidney (BHK) cell growth kinetics was investigated by using different kinetic model and the effect of glucose, glutamine, lactate and ammonia on BHK culture was studied.The obtained result showed that BHK cell growth and the products release kinetics obey logestic and ludking-piret models respectively and the corresponding parameters were evaluated in a suspension batch culture.
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