An investigation into the potential ability of iron oxide and g-C3N4 as photosensitizers in photodynamic therapy
An investigation into the potential ability of iron oxide and g-C3N4 as photosensitizers in photodynamic therapy
Navid Ghane1 Hossein Mahtabpour2
1) Sharif University of Technology, Tehran, Iran, Email:
2) Sharif University of Technology, Tehran, Iran, Email:
Publication :
2nd. International Congress on science & Engineering - paris(parisconf.com)
Abstract :
Photodynamic therapy (PDT) is becoming a promising method in cancer treatment owing to its noninvasive feature, high efficiency, and ideal accuracy. PDT technique highly relies on the level of reactive oxygen species (ROS) which produce in the process. In this study, Fe2O3 and g-C3N4 were synthesized through facile methods. Then the prepared samples were characterized by X-ray diffraction (XRD), Field Emission Scanning Electron Microscope (FESEM), Vibrating Sample Magnetometry (VSM), Brunauer-Emmett-Teller investigation (BET), ultraviolet-visible light (UV-Vis) and Photoluminescence (PL) spectra. Methylene blue (MB) degradation was also performed to identify which sample can generate more ROS. Iron oxide was magnetic with a higher specific surface area and its optical properties that are the light absorbance, and the separation of photoinduced charge carriers, were also better than g-C3N4. However, the photocatalytic activity of Fe2O3 in MB degradation under visible light irradiation was negligible in contrast, g-C3N4 was more active and consequently can produce a larger amount of ROS in PDT treatment.
Keywords :
iron oxide (Fe2O3)
graphitic carbon nitride (g-C3N4)
photodynamic therapy (PDT)
photocatalytic activity
reactive oxygen species (ROS)